The Need for Tamper-Resistant and Abuse-Deterrent Formulations
نویسندگان
چکیده
منابع مشابه
Abuse-deterrent and tamper-resistant opioid formulations: what is their role in addressing prescription opioid abuse?
About one in every three individuals will experience chronic pain in their lifetime, and opioids are known to be an effective means to treat this condition. Much attention, however, has been given to the fact that prescription opioid analgesics are some of the most frequently abused drugs, and misuse is prominent in patients with chronic pain. Several new opioid formulations that are designed t...
متن کاملAbuse-deterrent and tamper-resistant opioids: how valuable are novel formulations in thwarting non-medical use?
INTRODUCTION In recent years, attention has been given to the development of abuse-deterrent and tamper-resistant opioid formulations in light of concern over the growing misuse and abuse of opioids prescribed for the treatment of chronic pain. AREAS COVERED This critical review discusses abuse-deterrent and tamper-resistant formulations, which may help to overcome concerns of misuse in using...
متن کاملRoutes of Opioid Abuse and its Novel Deterrent Formulations
Despite the development and approval of abuse deterrent medications aiming to decrease the misuse of prescription opioids, abuse remains prevalent in the United States (U.S.) and abroad. Additionally, abusers have refined their tampering methods in order to bypass the advanced deterrent mechanisms of these novel formulation technologies [1,2]. Tampering with a medication can be done to assist i...
متن کاملCan abuse deterrent formulations make a difference? Expectation and speculation
It is critical that issues surrounding the abuse and misuse of prescription opioids be balanced with the need for these medications for the treatment of pain. One way to decrease the abuse of prescription opioid medications is to develop abuse deterrent formulations (or ADFs) that in some way prevent drug abusers from extracting out the active ingredient in order to employ alternate routes of a...
متن کاملAn iterative model for in vitro laboratory assessment of tamper deterrent formulations.
BACKGROUND In an effort to address the continuing problem of prescription opioid abuse, manufacturers are incorporating new technologies into formulations that are designed to deter product tampering and misuse. Standards for laboratory assessment of tamper deterrent properties of new formulations have not previously been developed. METHODS Experimental designs were developed for the in vitro...
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ژورنال
عنوان ژورنال: Journal of Pharmaceutical Care & Health Systems
سال: 2014
ISSN: 2376-0419
DOI: 10.4172/2376-0419.1000e102